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How Does Nattokinase Lower Heart Disease Risk?

nutritional values

In eastern Asia, natto (a soy-based Japanese food) has been very popular for a thousand years. Nattokinase is an enzyme found naturally in natto, and this enzyme is formed while natto is undergoing fermentation. Natto’s fermentation requires a unique bacterium known as Bacillus subtilis.

Consumption of natto has been related to an average longer lifespan of the Japanese population as it is said to lower chronic diseases. Specifically, studies and research prove that people who are involved with rich natto diets have lower tendencies of death from cardiac diseases.


The nattokinase health benefits and prominent smell and taste of natto come from its unique enzyme. While the soybeans are going through the fermentation process, the bacterium activates the nattokinase. This is how the manufacturing of nattokinase takes place, and it helps in giving the food its cheesy flavor along with a wide range of health benefits that are scientifically backed.


Nowadays, multiple health food specialty shops and grocery stores sell natto worldwide. People can buy homemade natto kits and consume nattokinase like a supplement.


A well-known, professional, and reliable supplier for raw materials of nattokinase is ‘Eiffel Biotech.’ They supply highly active nattokinase to significant health food companies and pharmaceutical factories. They are able to reach their highest activity from nattokinase 20000 FU/g to 50000 FU/g.


What are the nutritional values of nattokinase?
















Natto is very rich in vitamins, minerals, and protein. But, the majority of the health benefits of this food are bound to its dominant nattokinase enzyme. The enzyme nattokinase’s one and only food source is natto, but people can also purchase it as a supplement. Studies suggest that nattokinase supplements are as functional as directly consuming natto.




How does nattokinase lower the risks of heart disease?

Research has shown that the enzyme nattokinase helps in dissolving blood clots. This helps to maintain an exemplary structure of blood vessels, improves the flow of blood, lowers the blood pressure, reduces stress on the heart, and hence lowers the risk of cardiac disease.


Nattokinase enzymes promote an outstanding bacterial balance in the gut, which is also called the microbiome. Your immune system can turn weak due to poor gut health. It also increases the chances of chronic diseases such as diabetes, rheumatoid arthritis, cancer, obesity, and heart disease.


The other nattokinase health benefits are:


  • The probiotic properties of nattokinase boost your metabolism and help in reducing your body fat. It also potentially regulates and prevents diseases arising from metabolic disorders like obesity, heart disease, and diabetes.


  • Nattokinase is considered better than statin medications. The satin medicines initiate oxidative damage in your body, which lower energy levels and affect heart health. Nattokinase is a plant-based natural source that helps in lowering the lipid level in your body and prevents clogging of the blood vessels.


  • Nattokinase also helps lower the mucus viscosity and enables you to breathe better.


What are the unique features of nattokinase that help reduce risks related to heart diseases?

heart diseases

(CVD) Cardiovascular disease or heart disease is one of the leading causes of death in the whole world. The approach to managing and controlling heart disease mortality is hugely limited. The enzyme nattokinase (the most active component of natto) possesses numerous favorable effects on the cardiovascular system, and its consumption has been shown to reduce CVD mortality.


Eiffel Biotech provides genuine nattokinase products. Nattokinase is linked with activities like fibrinolytic, anti-atherosclerotic, anti-hypertensive, lipid-lowering, neuro-protective, and anti-platelet.


  • Nattokinase has both antithrombotic and fibrinolytic effects, which are very similar to the effects of heparin.


  • Nattokinase is capable of blocking the formation of thromboxane that, results in inhibition of clustering of the platelets without any fabrication of side effects related to bleeding.


  • Nattokinase is a potent antithrombotic element, and thus, by reducing the formation of thrombin, it is known to lower the progression rate of atherosclerotic lesions (reverse evolving) and plaque formation.


  • Oral administration of Nattokinase was proven to increase fibrinolytic activities in the blood plasma. It reduced ELT and increased the activity of tPA, thus, resulting in elevation of anticoagulation and thrombolysis profiles.


  • Nattokinase has an anti-atherosclerotic effect that is one of the main reasons for stroke and CVD. The lipid-lowering effect of nattokinase requires a comparatively longer treatment and a higher dosage.


  • Studies have shown that nattokinase has strong inhibitors that help to suppress ACE (angiotensin-converting enzyme). This essential enzyme is required for hypertensive peptide hormone production (angiotensin II). This helps to lower the rate of blood pressure in CVD patients.


  • Aspirin is widely used as a potent anti-coagulant that prevents atherothrombotic diseases, stroke, and heart attacks. However, long-term uses of aspirin generally come with GI (gastrointestinal) bleeding and side effects. Nattokinase can be an excellent alternative with no adverse side effects, and it is a naturally obtained source. Thus, it can be considered superior to aspirin.


  • Nattokinase can degrade amyloid fibrils at average body temperature and neutral pH and plays a role in treating amyloid-associated diseases like AD (Alzheimer’s disease). Cardiovascular or heart health is widely linked to brain health. Cardiac risk factors have an association with cognitive decline and Alzheimer’s disease.


  • In Japanese research, the manufacturing of nattokinase has been shown to prevent stroke progression in people with acute and ischemic stroke. It showed clear progression after oral administration of nattokinase.



End note


Low studies and research are why nattokinase is not yet registered as a potent drug. It is available as a nutritional supplement in the market. Nattokinase is a naturally derived element that has innumerable advantages. It is proven to be safe for consumption (for a long). Its routes of administration are primarily oral, but many anti-thrombotic drugs are often injected. It has numerous favorable cardiac effects, and it can be easily mass-produced.


Eiffel Biotech has been proven to be 100% genuine nattokinase products.


Multiple clinical tests and trials have been conducted, and they are still ongoing. Nattokinase health benefits are recommendable, and it is proven to be safe for oral and IV administration in the human body. The supplements are available in capsules or tablets for blood thinning, improved circulation, and prevention of blood clots.


Order now from Eiffel Biotech and take advantage of all the benefits nattokinase provides.